97 research outputs found

    Design of Adiabatic MTJ-CMOS Hybrid Circuits

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    Low-power designs are a necessity with the increasing demand of portable devices which are battery operated. In many of such devices the operational speed is not as important as battery life. Logic-in-memory structures using nano-devices and adiabatic designs are two methods to reduce the static and dynamic power consumption respectively. Magnetic tunnel junction (MTJ) is an emerging technology which has many advantages when used in logic-in-memory structures in conjunction with CMOS. In this paper, we introduce a novel adiabatic hybrid MTJ/CMOS structure which is used to design AND/NAND, XOR/XNOR and 1-bit full adder circuits. We simulate the designs using HSPICE with 32nm CMOS technology and compared it with a non-adiabatic hybrid MTJ/CMOS circuits. The proposed adiabatic MTJ/CMOS full adder design has more than 7 times lower power consumtion compared to the previous MTJ/CMOS full adder

    Identifikasi Kawasan Penangkapan Induk Udang Windu (Penaeus Monodon) pada Perairan Pesisir Kabupaten Aceh Jaya

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    Tujuan penelitian ini adalah untuk menetapkan kawasan penangkapan induk udang windu (Penaeus monodon) dan kondisi lingkungan perairannya ditinjau dari aspek fisika kimia perairan pada kawasan perairan kabupaten Aceh Jaya. Penelitian ini menggunakan pendekatan survey dan teknologi system informasi geografis. Kawasan penangkapan induk udang di Kabupaten Aceh Jaya pada umumnya terdapat pada titik ordinat: (1) H 950 34\u27 bujur timur dan 040 38\u27 lintang utara, (2) H 950 33\u27 bujur timur dan 040 39\u27 lintang utara, (3) H 950 34\u27 bujur timur dan 040 40\u27 lintang utara, (4) H 950 34\u27 bujur timur dan 040 33\u27 lintang utara. Parameter fisika kimia perairan yang diukur pada kawasan penangkapan induk udang menunjukkan kondisi yang sangat sesuai bagi sistem kehidupan udang.The aims of this study was to establish the broodstock catchment areas of tiger prawn (Penaeus monodon) and the condition of the waters which was surrounding their habitat in terms of environmental aspects of physical chemical water parameter in the coastal waters of Aceh Jaya region. This study used survey approach and geographic information system technology as methodelogy. The catching areas of broodstock in Aceh Jaya region commonly found on the ordinate point: (1) H 950 34\u27 east longitude and 040 38\u27 north, (2) H 950 33\u27 east and 040 39\u27 north, (3) H 950 34\u27 east and 040 40\u27 north, (4) H 950 34\u27 east and 040 33\u27 north. Physical and chemical parameters of water measured at catchment areas showed that the water parameters in the prawn habitat were very suitable for supporting of tiger prawn living

    Design of Integrated Ultra-Wideband (UWB) Bandpass Filter and U-Shape Defected Microstrip Structure DMS

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    Keywords: Ultra-Wideband, microstrip bandpass filter, notch response, defected microstrip structure (DMS). This paper presents a new class of a compact ultra-wideband (UWB) bandpass filter with Defected Microstrip Structure (DMS) to produce bandpass and band reject characteristics simultaneously. The bandpass filter produces a wideband frequency from 3.1 GHz to 10.6 GHz with a return loss, S 11 better than -15 dB and insertion loss, S 21 of around 0.1 db. While, the DMS exhibits a band reject response, better than -20 dB at a frequency of 5.78 GHz. Thus, the integrated BPF and DMS will produce wideband bandpass and band reject response simultaneously in the same structure. The design is simulated on a Roger Duroid RO4350 with a dielectric constant, εr of 3.48 and a thickness of 0.508 mm. The optimum topology of DMS with U-shape exhibits high selectivity, sharp response as well as high attenuation in the stopband. This new class design of Chebyshev bandpass filter with DMS is useful to remove any undesired signals in any ultra-wideband communication system

    Layered hydroxide anion exchanger and their applications related to pesticides: a brief review

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    Layered double hydroxides and layered hydroxide salts have generated enormous excitement in the inorganic field due to their potential to act as versatile host materials in fabricating novel host–guest layered materials. The ability of the layered hydroxide anion exchanger to be incorporated with a wide range of guest ions enable them to be exploited in various applications related to pesticides. This review sums up the different methods of preparing layered hydroxide anion exchanger, summarises the types of anion intercalated into these layered hydroxide anion exchanger based on their respective systems, and elucidates their potential applications in pesticide-related fields

    Tunnelling Methods and Hawking's radiation: achievements and prospects

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    The aim of this work is to review the tunnelling method as an alternative description of the quantum radiation from black holes and cosmological horizons. The method is first formulated and discussed for the case of stationary black holes, then a foundation is provided in terms of analytic continuation throughout complex space-time. The two principal implementations of the tunnelling approach, which are the null geodesic method and the Hamilton-Jacobi method, are shown to be equivalent in the stationary case. The Hamilton-Jacobi method is then extended to cover spherically symmetric dynamical black holes, cosmological horizons and naked singularities. Prospects and achievements are discussed in the conclusions.Comment: Topical Review commissioned and accepted for publication by "Classical and Quantum Gravity". 101 pages; 6 figure

    Behavior and Impact of Zirconium in the Soil–Plant System: Plant Uptake and Phytotoxicity

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    Because of the large number of sites they pollute, toxic metals that contaminate terrestrial ecosystems are increasingly of environmental and sanitary concern (Uzu et al. 2010, 2011; Shahid et al. 2011a, b, 2012a). Among such metals is zirconium (Zr), which has the atomic number 40 and is a transition metal that resembles titanium in physical and chemical properties (Zaccone et al. 2008). Zr is widely used in many chemical industry processes and in nuclear reactors (Sandoval et al. 2011; Kamal et al. 2011), owing to its useful properties like hardness, corrosion-resistance and permeable to neutrons (Mushtaq 2012). Hence, the recent increased use of Zr by industry, and the occurrence of the Chernobyl and Fukashima catastrophe have enhanced environmental levels in soil and waters (Yirchenko and Agapkina 1993; Mosulishvili et al. 1994 ; Kruglov et al. 1996)

    Graphene Oxide-Gallic Acid Nanodelivery System for Cancer Therapy

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    Despite the technological advancement in the biomedical science, cancer remains a life-threatening disease. In this study, we designed an anticancer nanodelivery system using graphene oxide (GO) as nanocarrier for an active anticancer agent gallic acid (GA). The successful formation nanocomposite (GOGA) was characterized using XRD, FTIR, HRTEM, Raman, and UV/Vis spectroscopy. The release study shows that the release of GA from the designed anticancer nanocomposite (GOGA) occurs in a sustained manner in phosphate-buffered saline (PBS) solution at pH 7.4. In in vitro biological studies, normal fibroblast (3T3) and liver cancer cells (HepG2) were treated with different concentrations of GO, GOGA, and GA for 72 h. The GOGA nanocomposite showed the inhibitory effect to cancer cell growth without affecting normal cell growth. The results of this research are highly encouraging to go further for in vivo studies

    Sustained release formulation of an anti-tuberculosis drug based on para-amino salicylic acid-zinc layered hydroxide nanocomposite

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    Background: Tuberculosis (TB), is caused by the bacteria, Mycobacterium tuberculosis and its a threat to humans since centuries. Depending on the type of TB, its treatment can last for 6-24 months which is a major cause for patients non-compliance and treatment failure. Many adverse effects are associated with the currently available TB medicines, and there has been no new anti-tuberculosis drug on the market for more than 50 year, as the drug development is very lengthy and budget consuming process.Development of the biocompatible nano drug delivery systems with the ability to minimize the side effects of the drugs, protection of the drug from enzymatic degradation. And most importantly the drug delivery systems which can deliver the drug at target site would increase the therapeutic efficacy. Nanovehicles with their tendency to release the drug in a sustained manner would result in the bioavalibilty of the drugs in the body for a longer period of time and this would reduce the dosing frequency in drug administration. The biocompatible nanovehicles with the properties like sustained release of drug of the target site, protection of the drug from physio-chemical degradation, reduction in dosing frequency, and prolong bioavailability of drug in the body would result in the shortening of the treatment duration. All of these factors would improve the patient compliance with chemotherapy of TB.Result: An anti-tuberculosis drug, 4-amino salicylic acid (4-ASA) was successfully intercalated into the interlamellae of zinc layered hydroxide (ZLH) via direct reaction with zinc oxide suspension. The X-ray diffraction patterns and FTIR analyses indicate that the molecule was successfully intercalated into the ZLH interlayer space with an average basal spacing of 24 Å. Furthermore, TGA and DTG results show that the drug 4-ASA is stabilized in the interlayers by electrostatic interaction. The release of 4-ASA from the nanocomposite was found to be in a sustained manner. The nanocomposite treated with normal 3T3 cells shows it reduces cell viability in a dose- and time-dependent manner.Conclusions: Sustained release formulation of the nanocomposite, 4-ASA intercalated into zinc layered hydroxides, with its ease of preparation, sustained release of the active and less-toxic to the cell is a step forward for a more patient-friendly chemotherapy of Tuberculosis

    Litterfall production in a tropical mangrove of Sarawak, Malaysia

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    Assessment of litterfall production is essential to ascertain the status of nutrient cycling and forest health. Sarawak, Malaysia, is endowed with numerous pristine and estuarine mangroves; however, research on primary productivity of these forests is scanty. Therefore, litterfall production in a pristine Sibuti mangrove of Sarawak was estimated using litter traps for one year (January–December 2013), and forest structure was studied through tree census. The forest was dominated by Rhizophora apiculata (relative density [RD] was 77.11%), followed by Xylocarpus granatum (RD was 16.92%) and other species (RD was only 5.97%). The annual dry weight of litterfalls was estimated to be 1640.82 g m−2, of which R. apiculata contributed 92.94%, followed by X. granatum (4.01%) and other species (3.05%). Leaves were the most abundant (57.21%) contributory component of litters, followed by propagules (11.89%), flowers (10.85%), twigs (8.56%), and stipules (8.45%). No significant correlations were found for total litterfall and its major components with climatic variables and forest structure. Total litterfall of R. apiculata and X. granatum did not show any seasonal variations. However, leaf litter of R. apiculata showed a significant seasonal variation between intermediate (January–April) and wet (September–December) seasons. The litterfall production of Sibuti mangrove forest is higher in comparison to other tropical mangroves of the world. The higher productivity of the forest could be due to nutrient availability, pristine nature, and stand maturity of the forest rather than climatic influences. The findings of the study suggest that litterfall production of the pristine Sibuti mangrove is not influenced by the variability of climatic factors

    Proteomics and in silico approaches to extend understanding of the glutathione transferase superfamily of the tropical liver fluke Fasciola gigantica

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    Fasciolosis is an important foodborne, zoonotic disease of livestock and humans, with global annual health and economic losses estimated at several billion US$. Fasciola hepatica is the major species in temperate regions, while F. gigantica dominates in the tropics. In the absence of commercially available vaccines to control fasciolosis, increasing reports of resistance to current chemotherapeutic strategies and the spread of fasciolosis into new areas, new functional genomics approaches are being used to identify potential new drug targets and vaccine candidates. The glutathione transferase (GST) superfamily is both a candidate drug and vaccine target. This study reports the identification of a putatively novel Sigma class GST, present in a water-soluble cytosol extract from the tropical liver fluke F. gigantica. The GST was cloned and expressed as an enzymically active recombinant protein. This GST shares a greater identity with the human schistosomiasis GST vaccine currently at Phase II clinical trials than previously discovered F. gigantica GSTs, stimulating interest in its immuno-protective properties. In addition, in silico analysis of the GST superfamily of both F. gigantica and F. hepatica has revealed an additional Mu class GST, Omega class GSTs, and for the first time, a Zeta class member
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